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SCIENCE

01

The device emits sound waves into the bone.

02

These waves reflect back and are captured by the device.

03

Advanced technology analyzes the signals to assess bone density and architecture.

How It Works

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What We Measure

Bone Density

Bone density (also called Bone Mineral Density or BMD) refers to the amount of bone mineral in your bones. It helps determine how strong and durable your bones are.

Why REMS Measures It:
REMS evaluates bone density without radiation, offering a safe, convenient way to monitor your bone health more frequently than traditional DXA scans.

 
T-Score Interpretation (from bone density results):
  • Normal: T-score ≥ -1.0
  • Osteopenia (low bone mass): T-score between -1.0 and -2.5
  • Osteoporosis: T-score ≤ -2.5z
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Fracture Risk Predicition

This is a calculated estimate of your likelihood to experience a fracture within the next 5 years.

Why REMS Measures It:
REMS combines your bone density, bone quality, and clinical factors (like age, gender, and health history) to offer a more personalized and accurate prediction than BMD alone.

Knowing your 5-year fracture risk helps guide your care plan—whether it’s lifestyle changes, supplements, or medical interventions.
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Fragility Score

The fragility score is a unique measurement provided by REMS that evaluates bone quality, not just density. It reflects how well the internal structure of your bone can resist fractures.

Why REMS Measures It:
Two people can have the same bone density but very different bone quality. This score helps assess how likely your bones are to break under minimal trauma, like a fall from standing height.
 
Fragility Score Interpretation:
  • Low Fragility (0-29): Healthy, strong bone structure
  • Moderate Fragility (30-49): Some weakening; increased risk of fracture
  • High Fragility (50-100): Significantly compromised bone structure; higher fracture risk
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Body Composition

Body composition measures the percentages of fat, muscle, and bone mass in your body. It gives a more detailed view of your overall health compared to just weight or BMI.

Why REMS Measures It: Muscle and fat distribution can impact bone health. For example, low muscle mass (sarcopenia) is linked to a higher risk of falls and fractures. Monitoring your composition helps support better decisions around nutrition, fitness, and treatment.
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REMS vs DXA
5 Key Benefits That Set REMS Apart from DXA

SUPPORTING STUDIES

An advanced quantitative echosound methodology for femoral neck densitometry

Ultrasound in Medicine & Biology, 2016

Key Finding: Introduced a novel REMS-based method for femoral neck densitometry, offering a non-ionizing alternative to DXA.

Could Radiofrequency Echographic Multi-Spectrometry (REMS) Overcome the Overestimation in BMD by Dual-Energy X-ray Absorptiometry (DXA) at the Lumbar Spine?

BMC Musculoskeletal Disorders, 2022

Key Finding: REMS improves osteoporosis diagnosis accuracy when lumbar spine BMD is artifactually high due to vertebral fractures or osteoarthritis.

Bone Health Status Evaluation in Men by Means of REMS Technology

Aging Clinical and Experimental Research, 2024

Key Finding: REMS demonstrates high diagnostic accuracy and precision in evaluating bone health in men, offering a reliable DXA alternative.

Radiofrequency echographic multi-spectrometry for the in-vivo assessment of bone strength: state of the art-outcomes of an expert consensus meeting organized by ESCEO

Aging Clinical and Experimental Research, 2019

Key Finding: Consensus established REMS as a promising technology for assessing bone strength and fracture risk non-invasively.

Radiofrequency echographic multi-spectrometry for the prediction of incident fragility fractures: A 5-year follow-up study

Bone, 2020

Key Finding: REMS predicted fragility fractures over a 5-year period as accurately as or better than traditional DXA.

Short-term monitoring of denosumab effect in breast cancer patients receiving Aromatase Inhibitors using REMS technology on lumbar spine

Annals of the Rheumatic Diseases, 2020

Key Finding: REMS successfully detected bone changes in breast cancer patients on denosumab and aromatase inhibitors.

Could Radiofrequency Echographic Multi-Spectrometry (REMS) Overcome the Limitations of BMD by DXA Related to Artifacts? A Series of 3 Cases

Journal of Ultrasound in Medicine, 2021

Key Finding: REMS provided accurate osteoporosis diagnosis in three cases where DXA results were artifactually elevated.

DXA Beyond Bone Mineral Density and the REMS Technique: New Insights for Current Radiologists Practice

La Radiologia Medica, 2024

Key Finding: REMS can overcome common DXA artifacts, providing more accurate BMD evaluations.

Fragility Score: a REMS-based indicator for the prediction of incident fragility fractures at 5 years

Aging Clinical and Experimental Research, 2023

Key Finding: The REMS-based Fragility Score successfully predicted fragility fractures at 5 years, enhancing fracture risk assessments.

Radiofrequency echographic multi-spectrometry compared with dual X-ray absorptiometry for osteoporosis diagnosis on lumbar spine and femoral neck

Osteoporosis International, 2019

Key Finding: REMS was shown to have comparable diagnostic performance to DXA, with advantages in artifact-prone regions.

Radiofrequency Echographic Multi Spectrometry (REMS) for the diagnosis of osteoporosis in a European multicenter clinical context

Bone, 2021

Key Finding: Confirmed REMS' accuracy and reproducibility for osteoporosis diagnosis in a broad European clinical setting.

DXA Errors Are Common and Reduced by Use of a Reporting Template

Journal of Clinical Densitometry, 2018

Key Finding: 92% of DXA reports had errors; 65% impacted diagnosis or treatment. Reporting templates reduced these errors.

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